Antifungal anadrol dosage agent for external application having a wide range of antifungal activity. At low concentrations terbinafine has fungicidal activity against dermatophytes (Trychophyton rubrum, Trychophyton mentagrophytes, Trychophyton verrucosum, Trychophyton violaceum, Trychophyton tonsurans, Microsporum canis, Epidermophyton floccosum), mold (mainly Candida albicans) and certain dimorphic fungi (Pityrosporum orbiculare). Activity against yeast fungi, depending on their type, may be a fungicidal or fungistatic.
Terbinafine specifically alters the early stage of the biosynthesis of sterols, occurring in fungi. This leads to a deficiency of ergosterol and to an intracellular accumulation of squalene, which causes death of fungal cells. Terbinafine action effected by the enzyme squalene epoxidase inhibiting located on the cell membrane of the fungus.
Terbinafine has no effect on the cytochrome P450 system in humans and, therefore, the metabolism of hormones or other drugs.
For external use absorption – less than 5%, has little systemic effect.
Prevention and treatment of fungal infections anadrol dosage of the skin, including foot mycoses ( “mushroom” of the foot), jock itch (tinea cruris), fungal lesions of the smooth skin of the body (tinea corporis), caused by such dermatophytes as by Trichophyton (including , Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton violaceum), Microsporum canis and Epidermophyton floccosum.
Yeast infections of the skin, mainly those caused genus Candida (e.g., Candida albicans), in particular diaper rash.
Colorful lichen (Pityriasis versicolor), called Pityrosporum orbiculare (also known as Malassezia furfur).
Hypersensitivity to terbinafine or to any of the auxiliary ingredients that make up the drug.
Hepatic and / or renal failure, alcoholism, depression of bone marrow hematopoiesis, tumors, metabolic diseases, limb occlusive vascular disease, children under 12 years of age (lack of sufficient clinical experience).
Pregnancy and lactation:
In experimental research teratogenic properties of terbinafine have been identified. So far no reports of any malformation when applying . However, as clinical experience with anadrol dosagein pregnant women is very limited, it should be used only on strict conditions.
Terbinafine is excreted in breast milk. However, in the case of nursing mother cream is absorbed through the skin, a small amount of active substances, so adverse effects on the infant is unlikely.
Dosage and administration:
Adults and children from 12 years.
Must be thoroughly clean and dry the affected area before applying the cream. The cream is applied 1 or 2 times per day to the affected thin layer of skin and adjacent portions of lightly rubbing. For infections involving intertrigo (under the breasts, in the interdigital spaces, between the buttocks, groin), cream application site can cover the gauze, especially at night.
The average duration of treatment is:
tinea torso, legs: 1 week; 1 times a day
tinea pedis: 1 week; 1 times a day
Skin candidiasis: 1-2 weeks; 1 or 2 times a day
pityriasis versicolor: 2 weeks; 1 or 2 times per day
Reducing the severity of clinical manifestations are usually noted in the first days of treatment. In the case of irregular or premature treatment termination there is a risk of renewed infection. If after 1-2 weeks of treatment were observed signs of improvement, there should be verification of the diagnosis.
Dosage cream in the elderly is not different from the above.
Children . We do not recommend the use of this drug in children under 12 years old.
Side effects :
redness, itching or stinging may occur at the site of the drug. Allergic reactions.
No cases of overdose have been reported. If accidentally anadrol dosage Cream will be accepted inside, one can expect the development of side effects: headache, nausea, epigastric pain and dizziness.Treatment : activated charcoal, if necessary – symptomatic supportive therapy.
There are no drug interactions cream is not known.